ABCG8 purified MaxPab mouse polyclonal antibody (B01P)
产品名称: ABCG8 purified MaxPab mouse polyclonal antibody (B01P)
英文名称: ABCG8 purified MaxPab mouse polyclonal antibody (B01P)
产品编号: H00064241-B01P
产品价格: null
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围:
亚诺法生技股份有限公司(Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse polyclonal antibody raised against a full-length human ABCG8 protein.
- Immunogen:
- ABCG8 (ADR83246.1, 1 a.a. ~ 673 a.a) full-length human protein.
- Sequence:
- MAGKAAEERGLPKGATPQHTSGLQDRLFSSESDNSLYFTYSGQPNTLEVRDLNYQVDLASQVPWFEQLAQFKMPWTSPSCQNSCELGIQNLSFKVRSGQMLAIIGSSGCGRASLLDVITGRGHGGKIKSGQIWINGQPSSPQLVRKCVAHVRQHNQLLPNLTVRETLAFIAQMRLPRTFSQAQRDKRVEDVIAELRLRQCADTRVGNMYVRGLSGGERRRVSIGVQLLWNPGILILDEPTSGLDSFTAHNLVKTLSRLAKGNRLVLISLHQPRSDIFRLFDLVLLMTSGTPIYLGAAQHMVQYFTAIGYPCPRYSNPADFYVDLTSIDRRSREQELATREKAQSLAALFLEKVRDLDDFLWKAETKDLDEDTCVESSVTPLDTNCLPSPTKMPGAVQQFTTLIRRQISNDFRDLPTLLIHGAEACLMSMTIGFLYFGHGSIQLSFMDTAALLFMIGALIPFNVILDVISKCYSERAMLYYELEDGLYTTGPYFFAKILGELPEHCAYIIIYGMPTYWLANLRPGLQPFLLHFLLVWLVVFCCRIMALAAAALLPTFHMASFFSNALYNSFYLAGGFMINLSSLWTVPAWISKVSFLRWCFEGLMKIQFSRRTYKMPLGNLTIAVSGDKILSAMELDSYPLYAIYLIVIGLSGGFMVLYYVSLRFIKQKPSQDW
- Host:
- Mouse
- Reactivity:
- Human
- Storage Buffer:
- In 1x PBS, pH 7.2
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody reactive against mammalian transfected lysate.
- Application Image
- Western Blot (Transfected lysate)
- Detection Antibody
- Entrez GeneID:
- 64241
- GeneBank Accession#:
- HQ258492.1
- Protein Accession#:
- ADR83246.1
- Gene Name:
- ABCG8
- Gene Alias:
- GBD4,MGC142217,STSL
- Gene Description:
- ATP-binding cassette, sub-family G (WHITE), member 8
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. The protein encoded by this gene functions to exclude non-cholesterol sterol entry at the intestinal level, promote excretion of cholesterol and sterols into bile, and to facilitate transport of sterols back into the intestinal lumen. It is expressed in a tissue-specific manner in the liver, intestine, and gallbladder. This gene is tandemly arrayed on chromosome 2, in a head-to-head orientation with family member ABCG5. Mutations in this gene may contribute to sterol accumulation and atherosclerosis, and have been observed in patients with sitosterolemia. [provided by RefSeq
- Other Designations:
- ATP-binding cassette sub-family G member 8,ATP-binding cassette, subfamily G, member 8,sterolin 2
- Gene Pathway
- Related Disease
- Atherosclerosis
- Atherosclerosis
- Biliary Tract Neoplasms
- Cardiovascular Diseases
- Cholelithiasis
- Coronary Artery Disease
- Coronary Disease
- Diseases in Twins
- Dyslipidemias
- Gallbladder Neoplasms
- Gallstones
- Genetic Predisposition to Disease
- Hypercholesterolemia
- Hyperlipidemias
- Hyperlipoproteinemia Type II
- Insulin Resistance
- Kidney Failure, Chronic
- Lung Neoplasms
- Metabolic Syndrome X