CIAP1 抗体
Applications
| In-house applications |
ELISA, IF, WB, IHC Application not tested? Please see our Guarantee. |
| Published applications |
IF, WB |
Publications |
6 citations –view here |
| Species specificity |
Human, Mouse; other species not tested. |
| Published Species |
Human, mouse, zebrafish |
|
Images
Prev12Next
 mouse skeletal muscle tissue were subjected to SDS PAGE followed by western blot with 10022-1-AP(cIAP1 antibody) at dilution of 1:1000 Immunohistochemical of paraffin-embedded human testis using 10022-1-AP(cIAP1 antibody) at dilution of 1:50 (under 10x lens) Immunohistochemical of paraffin-embedded human testis using 10022-1-AP(cIAP1 antibody) at dilution of 1:50 (under 40x lens) Immunofluorescent analysis of HepG2 cells, using BIRC2 antibody 10022-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).
|
| Positive WB detected in |
Mouse skeletal muscle tissue, Jurkat cells, mouse brain tissue, mouse liver tissue, mouse testis tissue |
| Positive IHC detected in |
Human testis tissue, human brain tissue, human kidney tissue, human ovary tissue, human pancreas tissue, human placenta tissue, human spleen tissue |
| Positive IF detected in |
HepG2 cells |
| Recommended dilution |
WB : 1:500-1:5000
IHC : 1:20-1:200
IF : 1:10-1:100 |
CIAP1 抗体Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
Product Information
| Source |
Rabbit |
Purification method |
Antigen affinity purification |
| Isotype |
IgG |
Storage |
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. |
Immunogen Information
| Immunogen |
CIAP1 fusion protein ag15203 |
Full name |
Baculoviral IAP repeat-containing 2 |
Calculated molecular
weight |
618aa,70 kDa |
Observed molecular
weight |
70 kDa, 55-60 kDa |
GenBank accession
number |
BC016174 |
Gene ID (NCBI) |
329 |
| Gene symbol |
BIRC2 |
Synonyms |
API1, BIRC2, C IAP1, cIAP1, Hiap 2, HIAP2, IAP 2, IAP homolog B, IAP2, MIHB, RING finger protein 48, RNF48 |
Background CIAP1 抗体
|
BIRC2 (also known as cIAP1) is a member of the inhibitor of apoptosis protein (IAP) family. The inhibitor of apoptosis (IAP) proteins are a family of anti-apoptotic regulators found in viruses and metazoans. BIRC2 is a nuclear shuttling protein, whose subcellular localization is mediated by the CRM1-dependent nuclear export pathway (PMID: 15265700). The protein is regulated transcriptionally and can be inhibited by mitochondrial proteins released in the cytoplasm upon apoptotic stimuli (PMID: 15187025). BIRC2 is also believed to be a critical regulator of vascular integrity and endothelial cell survival, thereby providing an additional target pathway for the control of angiogenesis and blood vessel homeostasis during embryogenesis, regeneration and tumorigenesis (PMID: 17934460). This BIRC2 antibody (10022-1-AP) can bind both full length (70kd) and cleaved form (60kd) of the protein. CIAP1 抗体
|
XY021Rb21 睫状神经营养因子(CNTF)单克隆抗体 Monoclonal Antibody to Ciliary Neurotrophic Factor (CNTF) Oryctolagus cuniculus (Rabbit)
XY022Ra21 血管内皮细胞蛋白C受体(PROCR)单克隆抗体 Monoclonal Antibody to Protein C Receptor, Endothelial (PROCR) Rattus norvegicus (Rat)
XY024Bo21 内分泌腺来源血管内皮生长因子(EG-VEGF)单克隆抗体 Monoclonal Antibody to Endocrine Gland Derived Vascular Endothelial Growth Factor (EG-VEGF) Bos taurus; Bovine (Cattle)
XY024Ra21 内分泌腺来源血管内皮生长因子(EG-VEGF)单克隆抗体 Monoclonal Antibody to Endocrine Gland Derived Vascular Endothelial Growth Factor (EG-VEGF) Rattus norvegicus (Rat)
XY025Bo21 嗜酸粒细胞趋化因子(ECF)单克隆抗体 Monoclonal Antibody to Eosinophil Chemotactic Factor (ECF) Bos taurus; Bovine (Cattle)
XY025Eq21 嗜酸粒细胞趋化因子(ECF)单克隆抗体 Monoclonal Antibody to Eosinophil Chemotactic Factor (ECF) Equus caballus; Equine (Horse)
XY025Gu21 嗜酸粒细胞趋化因子(ECF)单克隆抗体 Monoclonal Antibody to Eosinophil Chemotactic Factor (ECF) Cavia (Guinea pig )
XY025Ra21 嗜酸粒细胞趋化因子(ECF)单克隆抗体 Monoclonal Antibody to Eosinophil Chemotactic Factor (ECF) Rattus norvegicus (Rat)
XY025Si21 嗜酸粒细胞趋化因子(ECF)单克隆抗体 Monoclonal Antibody to Eosinophil Chemotactic Factor (ECF) Rhesus monkey (Simian)
XY027Ra21 红细胞生成素受体(EPOR)单克隆抗体 Monoclonal Antibody to Erythropoietin Receptor (EPOR) Rattus norvegicus (Rat)
XY028Ca21 红细胞生成素(EPO)单克隆抗体 Monoclonal Antibody to Erythropoietin (EPO) Canis familiaris; Canine (Dog)
XY028Eq21 红细胞生成素(EPO)单克隆抗体 Monoclonal Antibody to Erythropoietin (EPO) Equus caballus; Equine (Horse)
XY028Po21 红细胞生成素(EPO)单克隆抗体 Monoclonal Antibody to Erythropoietin (EPO) Sus scrofa; Porcine (Pig)
XY028Ra21 红细胞生成素(EPO)单克隆抗体 Monoclonal Antibody to Erythropoietin (EPO) Rattus norvegicus (Rat)
XY028Si21 红细胞生成素(EPO)单克隆抗体 Monoclonal Antibody to Erythropoietin (EPO) Rhesus monkey (Simian)
XY029Ca21 E选择素(SELE)单克隆抗体 Monoclonal Antibody to Selectin, Endothelium (SELE) Canis familiaris; Canine (Dog)
